AIS vs AIPO: Two AI ETFs With Very Different Definitions of the Theme
Both are AI-themed funds launched in 2025. AIS bets on the software and hardware driving the AI supercycle. AIPO bets on AI plus the power infrastructure needed to run it.
AIS (VistaShares Artificial Intelligence Supercycle ETF) and AIPO (Defiance AI and Power Infrastructure ETF) are both AI-themed ETFs, but they express the theme differently. AIS holds software, semiconductor, and cloud companies driving AI development — a concentrated growth bet on the companies building and selling AI capabilities. It charges 0.75% and has grown to $691M in assets. AIPO adds a layer that AIS does not: power infrastructure. Its mandate covers companies that both enable AI (chips, cloud) and those that power it (data center REITs, grid infrastructure, utilities with significant data center exposure). AIPO charges 0.69% and holds $756M. The key question is whether you believe AI's energy demand. Data centers currently consume roughly 2% of US electricity and are projected to reach 8% or higher by 2030 — represents a distinct investment opportunity. If yes, AIPO is the more differentiated fund. If you just want AI companies, AIS is the cleaner bet.
Both funds trade commission-free at every major brokerage. How the major brokerages compare →
📋 AIS vs AIPO — Key Facts Side by Side
| Metric | AIS | AIPO |
|---|---|---|
| Fund Name | VistaShares Artificial Intelligence Supercycle ETF | Defiance AI & Power Infrastructure ETF |
| Issuer | VistaShares | Defiance ETFs |
| Tracks Index | AI Supercycle Index (active methodology) | MarketVector US Listed AI and Power Infrastructure |
| Expense Ratio | 0.75% | 0.69% ✓ |
| Cost per $10K/yr | $75.00 | $69.00 |
| AUM | $969.8M | $958.0M |
| Holdings | 50 | 55 |
| Inception | 2025 | 2025 |
| 1-Year Return | +135.46% | +44.43% |
| 3-Year Return | — | — |
| 5-Year Return | — | — |
| Holdings Overlap | See holdings overlap → | |
| Avg Bid-Ask Spread | 0.03% | 0.03% |
Expense ratio, AUM, and returns updated Jul 22, 2026 from ETF BFF database. Returns are annualised. Not investment advice.
📊 AIS vs AIPO — Annualised Returns
Annualised returns (trailing, price-based). Past performance does not guarantee future results.
🎯 Which Fund Fits Which Investor?
- already use VistaShares and prefer staying within one fund family
- want the lowest fees: saves ~$6/yr per $10K vs AIS
- already use Defiance ETFs and prefer staying within one fund family
💰 What the Fee Difference Actually Costs
Adjust the numbers for your situation. This models each fund's expense ratio compounding against your balance over time.
Assumes a constant annual return reinvested, with each fund's expense ratio deducted yearly. Illustrative only; actual returns vary. Past performance does not guarantee future results.
🧩 What AIS and AIPO Actually Hold in Common
Among their top holdings, AIS and AIPO hold 2 of the same companies: Vertiv Holdings Co Class A, Advanced Micro Devices Inc.
- SK Hynix Inc 8.8%
- Micron Technology Inc 7.1%
- Advanced Micro Devices Inc • 5.0%
- Marvell Technology Inc 4.1%
- Silicon Motion Technology Corp ADR 3.7%
- Vertiv Holdings Co Class A • 3.6%
- Intel Corp 3.6%
- Taiwan Semiconductor Manufacturing Co Ltd ADR 3.3%
- Vicor Corp 2.8%
- Corning Inc 2.8%
- GE Vernova Inc 9.5%
- Vertiv Holdings Co Class A • 8.1%
- Eaton Corp PLC 8.0%
- Quanta Services Inc 7.8%
- Bloom Energy Corp Class A 5.1%
- Broadcom Inc 3.6%
- Cameco Corp 3.6%
- NVIDIA Corp 3.5%
- Constellation Energy Corp 3.2%
- Advanced Micro Devices Inc • 2.5%
Based on each fund's largest disclosed holdings. Names marked • are held by both. Weights shift over time. For overlap beyond the top holdings shown here, the holdings overlap tool shows the full picture.
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❓ AIS vs AIPO — Frequently Asked Questions
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